The purpose of this paper is to show the importance of new innovative technologies and new technological systems of active safety of vehicles, in contribution to improving road safety and sustainable mobility. Data at indicators point to an increase in mortality and deterioration of road safety. Current measures applied have not contributed to the expected improvement and reducing the number of deaths in traffic accidents. After making inquiries, among 50 potential measures of application of innovative technologies, the most effective measures can contribute to a significant reduction in the number of road accidents and the number of those killed in these accidents. Given the expected effect, reducing the mortality individual use from 7 % to 30 %, the best prospects for the application of intelligent systems have to adapt speed, automated emergency braking, warning in case of leaving the lane, Alcoholic switch and a reminder to use the safety belt. The results of application indicate the potential for improving road safety and sustainable mobility. Implementation of new technological systems of active safety of vehicles requires the adoption of legislation and establishing minimum common standards of installation in all Member States
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